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Roflumilast: A new phosphodiesterase 4 inhibitor for chronic obstructive pulmonary disease
Roflumilast is a novel, orally active phosphodiesterase 4 inhibitor currently under review by FDA for the treatment of patients with moderate-to-severe COPD.
Clinical News
Exenatide drug label to include information on post-marketing surveillance of altered kidney function
In early November 2009, FDA approved revisions to the drug label for exenatide (Byetta, Amylin Pharmaceuticals), an injectable glucagon-like peptide-1 agonist for the treatment of type 2 diabetes mellitus.
Study: Prescription patterns and predictors of aldosterone antagonist use in heart failure
Heart failure (HF) guideline-recommended aldosterone antagonist therapy was received by less than one-third of eligible patients participating in a quality improvement registry who had been hospitalized for HF.
Dabigatran compared to warfarin when given to patients with atrial fibrillation
Dabigatran, a new oral direct thrombin inhibitor, given to patients with atrial fibrillation at a dose of 110 mg was associated with rates of stroke and systemic embolism that were similar to those associated with warfarin, as well as lower rates of major hemorrhage.

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MEDWATCH DRUG SAFETY UPDATES
Tysabri (Natalizumab): Update of Healthcare Professional Information
Safesheath CSG Coronary Sinus Guide Hemostatic Introducer System with Infusion Sideport by Thomas Medical
Zyprexa (olanzapine): Use in Adolescents
Videx/Videx EC (didanosine): Labeling Revision - Risk of Non-Cirrhotic Portal Hypertension
Edwards Lifesciences Aquarius Hemodialysis System: Recall

Last updated on Fri Feb 05 11:00:00 EST 2010

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