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Feature Articles

Fampridine-SR: A potassium-channel blocker for the improvement of walking ability in patients with MS

October 1, 2009

Fampridine-SR is a sustained-release oral medication that is pending FDA approval for the symptomatic treatment of multiple sclerosis (MS).

Specialty pharmacy's role in REMS, FDA's new drug safety program

October 1, 2009

Specialty pharmacies are uniquely positioned to play a key role in the implementation of Risk Evaluation and Mitigation Strategies (REMS).

Golimumab: A human anti-TNF-alpha monoclonal antibody for the treatment of autoimmune joint diseases

September 1, 2009

Golimumab is a human anti-tumor necrosis factor (TNF)-alpha monoclonal antibody that was recently approved for the treatment of rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis.

P&T considerations in fashioning a knowledge base, action plan for cardiometabolic disorders and weight

September 1, 2009

The P&T committee is positioned to provide knowledge, strategies to improve treatment of patients with cardiometabolic disorders.

Rivaroxaban: A direct factor Xa inhibitor for VTE prophylaxis in patients undergoing total knee or hip replacement surgery

August 1, 2009

Rivaroxaban is a highly potent direct factor Xa inhibitor that is pending FDA approval for the indication of venous thromboembolism (VTE) prophylaxis in patients undergoing total knee replacement or total hip replacement surgery.

Emerging risk factors and risk markers for cardiovascular disease: Looking beyond NCEP ATP III

August 1, 2009

This review discusses emerging risk factors for CVD, including hs-CRP, lipoprotein(a), homocysteine, fibrinogen, homocysteine, and coronary artery calcification.

Milnacipran: A serotonin and norepinephrine reuptake inhibitor for the management of fibromyalgia syndrome

July 1, 2009

Milnacipran was recently approved by FDA for the management of fibromyalgia syndrome. Clinical trials have demonstrated that this agent may be a reasonable alternative or adjunct therapy for patients with fibromyalgia syndrome who are unable to tolerate first-line tricyclic antidepressant therapy.

Therapeutic considerations in managing multiple myeloma

July 1, 2009

This review highlights treatment guidelines, disease staging criteria, and new therapeutic approaches to MM, including an overview of supportive care and emerging pipeline agents.

Overview of depression and its management in children and adolescents

June 1, 2009

This review addresses the prevalence and management of major depressive disorder (MDD) in school-aged children and adolescents, including treatment guidelines and agents under investigation for this indication.

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