In the Pipeline - Formulary

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In the Pipeline

FDA Pipeline preview, October 2009 (Eplivanserin, Pancrelipase, Trabectedin, Clofarabine, Fampridine-SR, Collagenase clostridium histolyticum, Oxycodone reformulated, Pegylated interferon alfa-2b, Maraviroc, Armodafinil, Relaxin, Perifosine, Glycerol phenylbutyrate, Trabedersen)

November 1, 2009

Recent FDA action (through November 2009) related to Eplivanserin, Pancrelipase, Trabectedin, Clofarabine, Fampridine-SR, Collagenase clostridium histolyticum, Oxycodone reformulated, Pegylated interferon alfa-2b, Maraviroc, Armodafinil, Relaxin, Perifosine, Glycerol phenylbutyrate, Trabedersen.

FDA Pipeline preview, October 2009 (doxorubicin, trabectedin, carisbamate, alogliptin/pioglitazone, HPV vaccine, pralatrexate, romidepsin, hyaluronic acid, laromustine, clofarabine, prGCD, KNS-760704, rifaximin, hexvix, quinazoline495)

October 1, 2009

Recent FDA action (through October 2009) related to doxorubicin, trabectedin, carisbamate, alogliptin/pioglitazone, HPV vaccine, pralatrexate, romidepsin, hyaluronic acid, laromustine, clofarabine, prGCD, KNS-760704, rifaximin, hexvix, and quinazoline495

FDA Pipeline preview, September 2009 (cethromycin, pegloticase, guanfacine, denosumab, apaziquone, TZP-102, beclomethasone 17,21-dipropionate)

September 1, 2009

Recent FDA action (through September 2009) related to cethromycin, pegloticase, guanfacine, denosumab, apaziquone, TZP-102, and beclomethasone 17,21-dipropionate

Dirucotide trials for secondary progressive MS discontinued for lack of efficacy

August 18, 2009

Lilly and BioMS Medical reported that their investigational agent dirucotide did not meet the primary end point of delaying disease progression in patients with secondary progressive multiple sclerosis (SPMS) in the phase 3 MAESTRO-01 trial.

Development of bifeprunox for maintenance treatment of schizophrenia discontinued

August 18, 2009

Lundbeck and Solvay have announced that they are discontinuing development of bifeprunox for the maintenance treatment of schizophrenia.

Trial of sildenafil for PAH in patients with sickle cell disease terminated because of safety concerns

August 18, 2009

The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) has prematurely terminated a trial of sildenafil for the treatment of pulmonary arterial hypertension (PAH) in adult patients with sickle cell disease because of safety concerns.

FDA Pipeline preview, August 2009 (trazodone, casopitant, sertindole, alogliptin, bepotastine, trabectedin, velaglucerase alfa)

August 1, 2009

Recent FDA action (through August 2009) related to trazodone, casopitant, sertindole, alogliptin, bepotastine, trabectedin, and velaglucerase alfa

FDA Pipeline preview, July 2009 (bucindolol, botulinum toxin type A, rivaroxaban, quetiapine, olanzapine, ziprasidone, ofatumumab, pegloticase, pralatrexate, melphalan, paclitaxel)

July 1, 2009

Recent FDA action (through July 2009) related to bucindolol, botulinum toxin type A, rivaroxaban, quetiapine, olanzapine, ziprasidone, ofatumumab, pegloticase, pralatrexate, melphalan, and paclitaxel

FDA Pipeline preview, June 2009 (lucinactant, fenretinide, fampridine-SR, HPN-100, vitespen, prodarsan)

June 1, 2009

Recent FDA action (through June 2009) related to lucinactant, fenretinide, fampridine-SR, HPN-100, vitespen, and prodarsan

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